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Echographic features and perinatal outcomes in fetuses with congenital absence of ductus venosus
Author(s) -
GarciaDelgado Raquel,
GarciaRodriguez Raquel,
Romero Requejo Azahar,
Armas Roca Marta,
Obreros Zegarra Luciana,
Medina Castellano Margarita,
Garcia Hernandez Jose A.
Publication year - 2017
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.13176
Subject(s) - ductus venosus , medicine , fetus , umbilical vein , obstetrics , inferior vena cava , prenatal diagnosis , autopsy , pregnancy , cardiology , biochemistry , genetics , chemistry , biology , in vitro
The purpose of this study was to describe the echographic features and perinatal outcomes of fetuses with absence of ductus venosus. Material and methods Retrospective review of 10 cases with absence of ductus venosus diagnosed by prenatal ultrasonography between January 2014 and February 2016 at a single referral center. Prenatal findings, umbilical shunting type, perinatal outcomes, and autopsy reports were reviewed. Results A total of 11 491 fetuses underwent a first‐ and second‐trimester screening during the study period. Ten cases of absence of ductus venosus were diagnosed. All of the fetuses presented an extrahepatic shunt: three fetuses from the umbilical vein to the right atrium and the seven remaining fetuses from the umbilical vein to the inferior vena cava. Major structural defects and fetal effusions were detected in six fetuses. There were two cases of chromosomal abnormalities. Five patients underwent legal termination of pregnancy and five decided to carry to term. In two of these, the absence of ductus venosus anomaly was isolated and had a normal outcome. In the remaining three cases, a follow up of the children showed a variety of adverse outcomes. Conclusions The absence of ductus venosus is associated with high rates of adverse perinatal outcomes. The prognosis for this group of anomalies depends on the additional findings with targeted ultrasound. This pathology should lead to a detailed anatomical study and affected fetuses should be closely monitored for signs of congestive heart failure.

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