Open AccessReal‐world surgical outcomes of a gelatin‐hemostatic matrix in women requiring a hysterectomy: a matched case–control study
Author(s) -
Obermair Helena,
Janda Monika,
Obermair Andreas
Publication year - 2016
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.12924
Subject(s) - medicine , hysterectomy , adverse effect , surgery , hematoma , american society of anesthesiologists , abdominal hysterectomy
Abstract Introduction The aim of this study was to compare adverse events and surgical outcomes of hysterectomy with or without use of a gelatin‐hemostatic matrix ( SURGIFLO ® ). Materials and methods Prospective case–control study (Canadian Task Force classification II 2) of total hysterectomy (Piver Type 1) provided by surgeons in Australia between November 2005 and May 2015. Data were collected via SurgicalPerformance, a web‐based data project which aims to provide confidential feedback to surgeons about their surgical outcomes. Of 2440 records of women who received a hysterectomy, 1351 were eligible for these analyses; 107 received SURGIFLO ® hemostatic matrix to prevent postoperative blood loss and 1244 did not. Results Patients with or without SURGIFLO ® differed in age, Charlson comorbidity index, and American Society of Anesthesiologists physical status classification system score ( ASA ), and also differed in clinical outcomes. After matching for patient's age and ASA at surgery, patients with and without SURGIFLO ® had comparable baseline characteristics. Matched patients with and without SURGIFLO ® had comparable clinical outcomes including risk of developing vault hematoma, return to the operating room, transfusion of red cells, surgical site infection (pelvis), readmission within 30 days and unplanned ICU admission. Conclusions In a sample matched by age and ASA , SURGIFLO ® neither prevented nor caused additional adverse events in women undergoing hysterectomy. Surgeons used SURGIFLO ® more commonly among women who were older, had more comorbidities and a higher ASA score. This indicates that it may be most useful in complicated surgery or cases.