Open AccessCouples' willingness to donate embryos for research: a longitudinal study
Author(s) -
Samorinha Catarina,
Severo Milton,
Machado Helena,
Figueiredo Bárbara,
Freitas Cláudia,
Silva Susana
Publication year - 2016
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.12900
Subject(s) - medicine , embryo donation , donation , embryo transfer , fertility , psychosocial , in vitro fertilisation , demography , longitudinal study , gynecology , fertility clinic , embryo , obstetrics , population , environmental health , biology , pathology , psychiatry , sociology , economic growth , economics , microbiology and biotechnology
Abstract Introduction Decision‐making on embryo disposition is a source of distress and is subject to change over time. This paper analyzes the willingness of couples undergoing in vitro fertilization to donate cryopreserved embryos for research from 15 days after embryo transfer to 12 months later, taking into account the influence of psychosocial, demographic, and reproductive factors. Material and methods Prospective longitudinal study, with 74 heterosexual couples undergoing in vitro fertilization in a public fertility centre in Portugal, recruited between 2011 and 2012. Participants were evaluated twice: 15 days after embryo transfer and 12 months later. Results A significant decrease in patients' willingness to donate embryos for research over time was observed [86.5% to 73.6%; relative risk (RR) = 0.85; 95% CI 0.76–0.95]. A higher education level (>12 years) [adjusted RR (RR adj ) = 0.79; 95% CI 0.64–0.96], considering research on human embryos to be important (vs. very important) ( RR adj = 0.59; 95% CI 0.39–0.85) and practicing a religion less than once a month (vs. at least once a month) ( RR adj = 0.73; 95% CI 0.53–1.00) seemed associated with unwillingness to donate embryos for research over time. Change towards non‐donation happened mainly among couples who first considered that it was better to donate than wasting the embryos. Change towards donation occurred mostly among those stating that their priority at time 1 was to have a baby and who became pregnant in the meantime. Conclusions Quality of care guided by patients' characteristics, values, preferences, and needs calls for considering the factors and reasons underlying couples' willingness to donate embryos for research over time as a topic in psychosocial guidelines for infertility and medically assisted reproductive care.