Open AccessAssociation of dysmenorrhea with interstitial cystitis/bladder pain syndrome: a case–control study
Author(s) -
Chung ShiuDong,
Liu ShihPing,
Lin HerngChing,
Kang JiunnHorng
Publication year - 2014
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.12437
Subject(s) - medicine , odds ratio , interstitial cystitis , confidence interval , epidemiology , case control study , logistic regression , population , ambulatory , urinary system , environmental health
Objective Interstitial cystitis/bladder pain syndrome ( IC / BPS ) is a chronic disabling condition of the urological system. Many gynecological conditions are reported to be associated with IC / BPS . This study presents epidemiological evidence of a possible association between dysmenorrhea and IC / BPS , using population‐based data. Design A case–control study. Setting Taiwan. Sample The study sample was retrieved from Taiwan's Longitudinal Health Insurance Database 2000, i.e. 291 women aged 18–45 years with a diagnosis of IC / BPS between January 2000 and December 2010 (cases) and 873 randomly selected controls matched on age and index date of ambulatory care visit. We used logistic regression conditioned on age to calculate the odds ratio of cases having a prior diagnosis of dysmenorrhea relative to controls. Results Prior dysmenorrhea was found in 87 (29.9%) cases and in 163 (18.7%) of the controls. Conditional logistic regression showed a crude odds ratio of 1.86 (95% confidence interval 1.37–2.52, p < 0.001) for prior dysmenorrhea among cases vs. controls. The adjusted odds ratio was 1.59 (95% confidence interval 1.13–2.23, p = 0.007) after adjusting for medical co‐morbidities. Conclusion This population‐based study found that there is an association between IC / BPS and prior dysmenorrhea.