Open AccessA critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part II : the meta‐analyses
Author(s) -
Olofsson Per,
AyresdeCampos Diogo,
Kessler Jörg,
Tendal Britta,
Yli Branka M.,
Devoe Lawrence
Publication year - 2014
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.12412
Subject(s) - cardiotocography , randomized controlled trial , medicine , meta analysis , confidence interval , inclusion and exclusion criteria , obstetrics , pediatrics , pregnancy , fetus , pathology , genetics , alternative medicine , biology
We appraised the methodology, execution and quality of the five published meta‐analyses that are based on the five randomized controlled trials which compared cardiotocography ( CTG )+ ST analysis to cardiotocography. The meta‐analyses contained errors, either created de novo in handling of original data or from a failure to recognize essential differences among the randomized controlled trials, particularly in their inclusion criteria and outcome parameters. No meta‐analysis contained complete and relevant data from all five randomized controlled trials. We believe that one randomized controlled trial excluded in two of the meta‐analyses should have been included, whereas one randomized controlled trial that was included in all meta‐analyses, should have been excluded. After correction of the uncovered errors and exclusion of the randomized controlled trial that we deemed inappropriate, our new meta‐analysis showed that CTG + ST monitoring significantly reduces the fetal scalp blood sampling usage (risk ratio 0.64; 95% confidence interval 0.47–0.88), total operative delivery rate (0.93; 0.88–0.99) and metabolic acidosis rate (0.61; 0.41–0.91).