Lidocaine‐prilocaine ( EMLA ® ) cream as analgesia in hysteroscopy practice: a prospective, randomized, non‐blinded, controlled study

We investigated the efficacy of 5% lidocaine 25 mg–prilocaine 25 mg/g cream ( EMLA ® ) applied to the uterine cervix for reducing pain during diagnostic or operative hysteroscopy, using a visual analogue scale ( VAS ) for pain in a prospective randomized, non‐blinded, controlled study in 92 successive patients. Patients were randomized to either 3 mL of EMLA cream or 3 mL of ultrasound gel (placebo), placed endocervically and exocervically, 10 min before hysteroscopy. Intensity of pain was evaluated immediately after the procedure using a 10‐cm VAS . No differences were found between the two groups ( p  = 0.07). The number of women who wished to stop the procedure was significantly lower in the EMLA group compared with the control group ( p  = 0.013). We concluded that topical instillation of EMLA does not decrease pain during hysteroscopy, but does reduce a desire to abandon the procedure.