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HISTOGENESIS OF ARTERIAL INTIMAL HYPERPLASIA AND ATHEROSCLEROSIS
Author(s) -
TENNANT MARC,
DILLEY RODNEY J.,
MCGEACHIE JOHN K.,
PRENDERGAST FRANCIS J.
Publication year - 1990
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/ans.1990.60.2.79
Subject(s) - intimal hyperplasia , histogenesis , medicine , smooth muscle , hyperplasia , pathology , endothelium , immunohistochemistry
This article briefly reviews the histological evidence for the genesis of intimal hyperplasia and atherosclerosis in arteries. It concentrates upon the origin, structure and behaviour of vascular smooth muscle cells in the intimal (subendothelial) layer. The interactions between these intimal muscle cells, the endothelium and the blood are discussed with particular reference to their role in the histogenesis of intimal hyperplasia and atherosclerosis.