Premium
Comparison of metal stents versus plastic stents for preoperative biliary drainage: a meta‐analysis of five randomized controlled trials
Author(s) -
Zhang Wei,
Xu Lin,
Che Xu
Publication year - 2021
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.16899
Subject(s) - medicine , randomized controlled trial , relative risk , confidence interval , surgery , stent , biliary drainage , pancreatitis , biliary stent
Background Although routine preoperative biliary drainage (PBD) is generally not recommended for patients with malignant distal biliary obstruction (MDBO), it is still necessary in many cases. The objective of this study is to compare the effects of metal stents (MSs) and plastic stents (PSs) on PBD in patients with MDBO. Methods All the randomized controlled trials (RCTs) that compared MS with PS for PBD and published from the date of database establishment to September 2020 were identified by searching the PubMed, EMBASE and Cochrane databases. Results Five RCTs involving 445 patients were included. There were 201 cases in the MS group, with 244 in the PS group. Re‐interventions (relative risk (RR) = 0.40, 95% confidence interval (CI) 0.21–0.75, P = 0.004), stent occlusions (RR = 0.36, 95% CI 0.18–0.75, P = 0.006), postoperative complications (RR = 0.76, 95% CI 0.59–0.97, P = 0.03) and preoperative cholangitis (RR = 0.19, 95% CI 0.05–0.78, P = 0.02) were lower in the MS group than in the PS group. Preoperative pancreatitis (RR = 2.11, 95% CI 1.06–4.19, P = 0.03) was higher in the MS group than in the PS group. No significant difference was observed in the overall preoperative complications, postoperative pancreatic fistulas, delayed gastric emptying, wound infections and postoperative bleeding between these two groups. Conclusions MS and PS exerted a similar effect on PBD, but PS had a higher risk of preoperative stent obstruction and postoperative complications, requiring more frequent interventions preoperatively. However, larger sample and higher quality RCTs are necessary for further verification.