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Nodal metastasis size predicts disease‐free survival in cutaneous head and neck squamous cell carcinoma involving the parotid but not cervical nodes
Author(s) -
Sood Ashish,
Wykes James,
McGuinness John,
Fowler Allan,
Ebrahimi Ardalan
Publication year - 2020
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.16413
Subject(s) - medicine , hazard ratio , confidence interval , proportional hazards model , oncology , multivariate analysis , lymph node , neck dissection , metastasis , head and neck squamous cell carcinoma , radiation therapy , head and neck cancer , carcinoma , surgery , cancer
Nodal metastatic size significantly predicts disease‐free survival on multivariate analysis, with the prognostic impact predominantly occurring in parotid metastases. Each 1 cm increase in the size of nodal metastasis increased the risk of recurrence or death by 27%. Parotid nodal metastasis size thresholds of <3, 3–4.5 and > 4.5 cm optimized prognostic discrimination.