Premium
Elevated visceral fat area is associated with adverse postoperative outcome of radical colectomy for colon adenocarcinoma patients
Author(s) -
Zhai TingShuai,
Kang Yuan,
Ren WenHao,
Liu Qi,
Liu Chao,
Mao WeiZheng
Publication year - 2019
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.15283
Subject(s) - medicine , body mass index , adenocarcinoma , visceral fat , colectomy , obesity , stage (stratigraphy) , gastroenterology , colon adenocarcinoma , surgery , colorectal cancer , insulin resistance , cancer , paleontology , biology
Objective To assess the impact of visceral obesity quantified by preoperative computed tomography on short‐term postoperative outcomes compared with body mass index (BMI) in stage I–III colon adenocarcinoma patients. Methods In this retrospective study, 107 patients treated with radical colectomy for stage I–III colon adenocarcinoma were classified as obese or non‐obese by computed tomography‐based measures or BMI (obese: BMI ≥28 kg/m 2 , visceral fat area (VFA) to subcutaneous fat area ratio (V/S) ≥0.4, and VFA ≥100 cm 2 ). Clinical variables, operation time, estimated blood loss, pathologic stage, histologic grade, postoperative complications, postoperative stay and hospitalization expenses were compared. Results Obese patients by VFA were more likely to have higher postoperative complication rate (32.9 versus 11.8%, P = 0.021), have longer operation time (184.6 ± 49.5 versus 163.1 ± 44.1 min, P = 0.033), postoperative stay (15.21 ± 7.59 versus 12.29 ± 5.40 days, P = 0.047) and cost more ($10 758.7 ± 3271.7 versus $9232.0 ± 2994.6, P = 0.023) than non‐obese. Conclusion Visceral obesity graded by VFA is associated with increased postoperative morbidity, operation time, postoperative stay and hospitalization expenses for colon adenocarcinoma patients and may be superior to BMI or V/S for the prediction of colon surgery.