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Suspended animation: the past, present and future of major cardiothoracic trauma
Author(s) -
Mohiyaddin Syed,
Nanjaiah Prakash,
Saad Ahmed O.,
Acharya Metesh N.,
Khan Tanveer A.,
Davies Rhodri H.,
Ashraf Saeed
Publication year - 2017
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.14313
Subject(s) - medicine , resuscitation , cardiopulmonary resuscitation , clinical trial , hypothermia , intervention (counseling) , food and drug administration , intensive care medicine , medical emergency , emergency medicine , anesthesia , nursing
About 50% of the trauma victims die at the scene mostly because of exsanguinating haemorrhage. Most trials of resuscitation fail in face of the ongoing bleeding. Ongoing research/studies to save these victims by inducing rapid hypothermia using cardiopulmonary bypass as an emergency initial measure along with delayed resuscitation show improved outcomes. A comprehensive review of this research and analysis of studies showed that rapid induction of hypothermia within 5 min of cardiac arrest is associated with better survival and improved neurological outcome. This led us to conclude that suspended animation is a lifesaving modality for the treatment of trauma victims, otherwise hurtling towards certain death. This should be integrated into regular clinical practice. The US Food and Drug Administration has given its approval for clinical trials on such an intervention.