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Age 80 years and over is not associated with increased morbidity and mortality following pancreaticoduodenectomy
Author(s) -
Kim Sandy Y.,
Fink Michael A.,
Perini Marcos,
Houli Nezor,
Weinberg Laurence,
Muralidharan Vijayaragavan,
Starkey Graham,
Jones Robert M.,
Christophi Christopher,
Nikfarjam Mehrdad
Publication year - 2018
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.14039
Subject(s) - medicine , pancreaticoduodenectomy , american society of anesthesiologists , complication , surgery , mortality rate , rehabilitation , pediatrics , physical therapy , resection
Background Pancreaticoduodenectomy ( PD ) is associated with high morbidity, which is perceived to be increased in the elderly. To our knowledge there have been no Australian series that have compared outcomes of patients over the age of 80 undergoing PD to those who are younger. Methods Patients who underwent PD between January 2008 and November 2015 were identified from a prospectively maintained database. Results A total of 165 patients underwent PD of whom 17 (10.3%) were aged 80 or over. The pre‐operative health status, according to American Society of Anesthesiologists class was similar between the groups ( P = 0.420). The 90‐day mortality rates (5.9% in the elderly and 2% in the younger group; P = 0.355) and the post‐operative complication rates (64.7% in the elderly versus 62.8% in the younger group; P = 0.88) were similar. Overall median length of hospital stay was also similar between the groups, but older patients were far more likely to be discharged to a rehabilitation facility than younger patients (47.1 versus 12.8%; P < 0.0001). Older patients with pancreatic adenocarcinoma ( n = 10) had significantly lower median survival than the younger group ( n = 69) (16.6 versus 22.5 months; P = 0.048). Conclusion No significant differences were seen in the rate of complications following PD in patients aged 80 or over compared to younger patients, although there appears to be a shorter survival in the elderly patients treated for pancreatic cancer. Careful selection of elderly patients and optimal peri‐operative care, rather than age should be used to determine whether surgical intervention is indicated in this patient group.