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Baseline quality of life predicts pelvic exenteration outcome
Author(s) -
Choy Ian,
Young Jane M.,
BadgeryParker Tim,
Masya Lindy M.,
Shepherd Heather L.,
Koh Cherry,
Heriot Alexander G.,
Solomon Michael J.
Publication year - 2017
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.13419
Subject(s) - medicine , pelvic exenteration , quality of life (healthcare) , surgery , prospective cohort study , nursing
Background Recurrent rectal cancer affects a significant group of patients with no current consensus on management. This study investigated patients' quality of life ( QoL ) in the 12 months after pelvic exenteration. Method Prospective cohort study with clinical and QoL data collected at baseline and 1, 3, 6, 9 and 12 months. QoL trajectories were modelled over 12 months from date of discharge using linear mixed models. Results Of 117 patients, 93 underwent pelvic exenteration surgery, 24 did not. Thirty‐day mortality was nil for both groups. For patients who had surgery, 15 (16%) died within 12 months of surgery compared with nine (38%) of the non‐surgery group. Baseline QoL scores were highly variable. The non‐exenteration patients' QoL gradually declined over 12 months while exenteration patients declined then recovered. Patients with high baseline QoL scores remained high, and those with low baseline QoL remained low. Baseline QoL score, gender and bony resection were significant predictors of QoL score at 12 months. Conclusion Baseline QoL is a significant, independent predictor of patients' QoL after pelvic exenteration for recurrent rectal cancer.