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Risk factors of delayed gastric emptying following pancreaticoduodenectomy
Author(s) -
Liu QiYu,
Li Li,
Xia HongTian,
Zhang WenZhi,
Cai ShouWang,
Lu ShiChun
Publication year - 2014
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.12850
Subject(s) - medicine , pancreaticoduodenectomy , pancreatic fistula , univariate analysis , gastric emptying , logistic regression , univariate , body mass index , multivariate analysis , incidence (geometry) , abdominal surgery , multivariate statistics , risk factor , gastroenterology , surgery , stomach , pancreas , statistics , physics , mathematics , optics
Background This study aims to explore the morbidity and risk factors of delayed gastric emptying ( DGE ) following pancreaticoduodenectomy. Methods Between 1 J anuary 2013 and 31 D ecember 2013, data from 196 consecutive patients who underwent pancreaticoduodenectomy in the C hinese PLA G eneral H ospital were recorded retrospectively. A total of 17 factors were examined with univariate analysis, and multivariate logistic regression analysis was used to estimate relative risks. Results DGE occurred in 71 patients (36.2%). The incidence rates of grade A , grade B and grade C DGE were 22.4% (44/196), 6.1% (12/196) and 7.7% (15/196), respectively. There were three post‐operative deaths for the entire series, with an overall mortality rate of 1.5%. Braun enteroenterostomy, clinically relevant post‐operative pancreatic fistula ( CR ‐ POPF ) and intra‐abdominal collection correlated with DGE rates significantly in univariate analysis, whereas CR ‐ POPF and intra‐abdominal collection were independent risk factors in multivariate logistic regression analysis. Body mass index ≥25 kg/m 2 , CR ‐ POPF and intra‐abdominal collection correlated with clinically relevant DGE rates significantly and were independent risk factors in univariate analysis and multivariate regression. Conclusion Only post‐operative complications instead of operative methods were associated with DGE . Early diagnosis and timely treatment for pancreatic fistula and intra‐abdominal collection were helpful to decrease morbidity and promote recovery of DGE .