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Tuberculosis cervical lymphadenopathy mimics lateral neck metastasis from papillary thyroid carcinoma
Author(s) -
Kim SeokMo,
Jun Hak Hoon,
Chang HoJin,
Chun Ki Won,
Kim BupWoo,
Lee Yong Sang,
Chang HangSeok,
Park Cheong Soo
Publication year - 2016
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.12727
Subject(s) - medicine , cervical lymphadenopathy , tuberculosis , thyroid carcinoma , metastasis , pathology , dermatology , thyroid , disease , cancer
Background Tuberculosis ( TB ) lymphadenitis is a frequent cause of lymphadenopathy in areas in which TB is endemic. Cervical lymphadenopathy in TB can mimic lateral neck metastasis ( LNM ) from papillary thyroid carcinoma ( PTC ). This study evaluated the clinicopathological features of patients with PTC and TB lateral neck lymphadenopathy. Methods Of the 9098 thyroid cancer patients who underwent thyroid cancer surgery at the Thyroid Cancer Center of Gangnam Severance Hospital between January 2009 and April 2013, 28 had PTC and showed TB lymphadenopathy of the lateral neck node. The clinicopathological features of these 28 patients were evaluated. Results Preoperatively, all 28 patients were diagnosed with PTC and showed cervical lymphadenopathy. All had radiological characteristics suspicious of metastasis in lateral neck nodes. Based upon the results from intraoperative frozen sections, lymph node dissection ( LND ) was not performed on 19 patients. Seven of eight patients who underwent LND had metastasis combined with tuberculous lymphadenopathy, with the remaining patient negative for LNM . Conclusions Intraoperative sampling and frozen sectioning of lymph nodes suspicious of metastasis can help avoid unnecessary LND for tuberculous lymphadenopathy.