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Analysis of 35 cases of X anthogranulomatous pyelonephritis
Author(s) -
Addison Ben,
Zargar Homayoun,
Lilic Nikola,
Merrilees David,
Rice Michael
Publication year - 2015
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.12581
Subject(s) - medicine , xanthogranulomatous pyelonephritis , retrospective cohort study , histopathology , nephrectomy , population , cohort , presentation (obstetrics) , surgery , pediatrics , kidney , pathology , environmental health
Background To retrospectively determine key demographic and clinical features of 35 patients with X anthogranulomatous pyelonephritis ( XGP ) in a N ew Z ealand setting and to compare it with the existing literature. Methods A retrospective review of patients having a confirmed diagnosis of XGP on histopathology examination was performed. Key clinical and demographic features were analysed and compared with the published literature. Results XGP was diagnosed in 35 patients over a 12‐year (2001–2013) period in A uckland P ublic H ospital. Ninety‐one percent of the patients were female. The population had significantly higher numbers of M aori and P acific I sland patients compared with the general population (74%). Staghorn calculi were the most common cause (51.4%) with obstructing ureteric calculi as the next most common (22.9%) cause. Twenty percent of cases were not thought to be XGP prior to nephrectomy (suspicious renal mass). Thirteen (38%) patients suffered serious complications post‐operatively ( C lavien 3–5). Conclusion XGP is a rare chronic inflammatory condition that appears to be overrepresented by M aori and P acific islanders in our cohort when compared with the overall patient pool. Surgical treatment is associated with significant morbidity but remains the only definitive option. Obesity and other conditions associated with metabolic syndrome may coexist at the time of presentation and may be contributing factors to the development of XGP and poor outcomes associated with it.