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Gallbladder carcinoma: a N ew Z ealand centre's 10‐year experience with presentation, ethnic diversity and survival rate
Author(s) -
Lilic Nikola,
Addison Ben,
Hammodat Hisham
Publication year - 2015
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.12503
Subject(s) - medicine , gallbladder cancer , gallbladder , carcinoma , incidence (geometry) , gastroenterology , cancer , malignancy , population , surgery , physics , environmental health , optics
Background Gallbladder cancer is a high‐mortality cancer with a wide range of incidence worldwide. Some indigenous populations are known to have a higher incidence of gallbladder cancer. Commonly, it is incidentally discovered during routine gallbladder surgery. The primary aim was to determine the incidence and characteristics of gallbladder cancer in a N ew Z ealand population. The secondary aim was to determine if inequalities in gallbladder cancer rates between Mā ori and non‐Mā ori have decreased. Methods A retrospective cohort study utilizing an online database was conducted to identify all patients with gallbladder malignancy treated in the W aitemata D istrict H ealth B oard from 2003 to 2013. The outcomes measured were staging of cancer, histology, ethnicity, incidental finding and survival rates. Results The age‐standardized incidence ( ASI ) rate of gallbladder carcinoma is 0.60/100 000. The gender‐specific ASI rates were 0.21/100 000 (men) and 0.76/100 000 (women). The incidence for Mā ori was 0.96/100 000 (men) and 1.37/100 000 (women). Gallbladder carcinoma was found incidentally in 0.44% of cholecystectomies, which made up 46.2% of all cases. Right upper quadrant pain was the most common presenting symptom (74.4%). Surgery was the most common treatment modality (66.7%). Mean survival across all patients was 12.24 months. Conclusion Our study found that the ASI of gallbladder carcinoma when compared with the K oea et al . study has decreased for men from N ew Z ealand, but appears to have increased slightly for women from N ew Z ealand. The raw incidence for Mā ori men and women appears to have decreased, but inequality in gallbladder cancer incidence between Mā ori and non‐ Mā ori remains.