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Comparison between two types of local resection in the treatment of ampullary cancer
Author(s) -
Zhao XiangQian,
Huang XiaoQiang,
Zhang WenZhi,
Liu Zhe
Publication year - 2014
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1111/ans.12047
Subject(s) - medicine , pathological , surgery , resection , metastasis , retrospective cohort study , cancer , biopsy , blood loss , distant metastasis , complication , radiology
Background This study aims to compare the effects of two different local resection procedures on the prognosis of ampullary cancer. Methods We carried out a retrospective study using clinical and pathological data from patients with ampullary cancer who underwent local resection between F ebruary 1996 and F ebruary 2009 in the PLA G eneral H ospital. In these participants, we carried out a comparative analysis between the transduodenal (the transduodenal group) and the extraduodenal (extraduodenal group) surgical approaches. Results No significant differences in gender, age, preoperative bilirubin levels, CA 19‐9 values, biopsy results, tumour size, differentiation status, degree of invasion, surgical margins, recurrence, metastasis and complication rates, and intraoperative blood loss were found. As compared to the transduodenal group, the extraduodenal group showed a longer duration of surgery and higher survival rates. Conclusions Even though the operation time for the extraduodenal resection of ampullary cancer was longer, the survival rate was higher than in patients who underwent transduodenal resection. For certain patients, the extraduodenal approach may be more appropriate when technical conditions allow it.