Open AccessAnkyrin‐2 genetic variants: A case of Ankyrin‐B syndrome
Author(s) -
Song Jin,
Sasmita Bryan Richard,
Deng GuoLan
Publication year - 2022
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12933
Subject(s) - ankyrin , medicine , sudden cardiac death , ankyrin repeat , cardiology , dysautonomia , sudden death , genetics , gene , disease , biology
Inherited cardiac arrhythmias (ICA) have become one of the leading causes of sudden cardiac death in people under 40 years old. Variants in the ankyrin‐B or ankyrin‐2 genes will result in several cardiac arrhythmias ranging from sinus node dysfunction to life‐threatening arrhythmias. In this case study, we report a typical ankyrin‐2 variant, in which ventricular tachyarrhythmias might be reproduced through exercise or stress tests.