Open AccessShould beta‐blockers be continued as a treatment for myocardial infarction in the case of Kounis syndrome?
Author(s) -
Amino Mari,
Fukushima Tomokazu,
Uehata Atsushi,
Nishikawa Chiemi,
Morita Seiji,
Nakagawa Yoshihide,
Murakami Tsutomu,
Yoshioka Koichiro,
Ikari Yuji
Publication year - 2021
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12837
Subject(s) - medicine , kounis syndrome , anaphylaxis , myocardial infarction , cardiogenic shock , cardiology , beta blocker , shock (circulatory) , carvedilol , beta (programming language) , anaphylactic shock , acute coronary syndrome , anesthesia , allergy , heart failure , immunology , computer science , programming language
A 71‐year‐old male patient reported to our hospital with anaphylactic shock, and the following two issues were focused in this case. First, he was resistant to adrenaline because of taking beta‐blocker, and shock was repeated until glucagon administration was initiated. Second, he developed acute coronary syndrome. Two mechanisms contributing to Kounis syndrome were differentiated: 1) adrenaline induced coronary spasm and platelet activation or 2) a mismatch between oxygen supply and demand due to an allergic reaction. Beta‐blocker therapy was discontinued because his cardiac function was preserved. Secondary preventive beta‐blockers in recovering myocardial infarction with severe anaphylaxis history should be carefully considered.