Open AccessValue of ST‐segment change in lead aVR in diagnosing left main disease in Non‐ST‐elevation acute coronary syndrome—A meta‐analysis
Author(s) -
Lee GienKuo,
Hsieh YenPing,
Hsu ShangWei,
Lan ShouJen,
Soni Kshitij
Publication year - 2019
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12692
Subject(s) - medicine , cardiology , odds ratio , myocardial infarction , acute coronary syndrome , confidence interval , meta analysis , coronary artery disease , lead (geology) , incidence (geometry) , st segment , geomorphology , geology , physics , optics
Background Previous researches proved that the ST‐segment elevation (STE) in lead aVR had great significance on the prediction of severe left main lesion or serious multivessel lesions. The current research is to summarize the published data and evaluate the overall association of STE in lead aVR and left main coronary artery disease (LMD) in Non‐ST‐elevation acute coronary syndrome. Methods Literature searching was performed in the online database, and a systematic review was conducted based on the searched results. Meaningful STE in lead aVR was summarized and analyzed for odds ratio (OR) and 95% confidence intervals (95% CI). Results Twenty‐seven articles were included for final data analysis. Compared with STE < 0.05, STE ≥ 0.05 mV was associated with a higher incidence rate of LMD (OR = 6.64, 95% CI: 4.80 ~ 9.17), and the degree of STE in lead aVR was significantly associated with LMD. Myocardial infarction was more likely to occur in patients with STE ≥ 0.05 mV than in patients with STE < 0.05 mV (OR = 3.12, 95% CI: 1.73 ~ 5.62). Conclusions The STE in lead aVR and the degree of STE are independent predictors in diagnosing LMD or myocardial infarction.