Open AccessThe value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome
Author(s) -
Cirakoglu Omer Faruk,
Aslan Ahmet Oğuz,
Akyuz Ali Riza,
Kul Selim,
Şahin Sinan,
Korkmaz Levent,
Sayın Muhammet Raşit
Publication year - 2019
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12622
Subject(s) - medicine , atrial fibrillation , interquartile range , cardiology , confidence interval , acute coronary syndrome , coronary artery disease , ejection fraction , heart failure , myocardial infarction
Abstract Background and aim New‐onset atrial fibrillation (NOAF) has been associated with poor outcome in patients with acute coronary syndromes (ACS). Also, Syntax score (SS) is a scoring system that is derived from angiographic images and is associated with long‐term mortality and major adverse cardiac events. In this study, we aimed to assess the relationship between SS and NOAF with known predictors of atrial fibrillation. Methods In a prospective, single‐center, cross‐sectional study, 692 patients who were diagnosed with coronary artery disease for the first time were enrolled consecutively. NOAF was defined as atrial fibrillation, which was documented after hospital admission. SS was calculated by a computer software. Multivariable logistic regression analyzes were used to detect the relationship between variables and NOAF. Results New‐onset atrial fibrillation was detected in 82 patients (11.8%). Patients with NOAF had higher SS (22, interquartile range 18.3–25.1, vs. 12, interquartile range 7–19.5, p < 0.001). According to multivariable logistic regression analysis for NOAF, SS were independently and significantly associated (OR, 1.103; 95% confidence interval, 1.047–1.163; p < 0.001). Other independent predictors of NOAF were TIMI flow <3, C reactive protein, left ventricular ejection fraction, left atrial volume index and E/E′ ratio. The optimal cut‐off value for SS was 18 for the development of NOAF with 82% sensitivity and 68% specificity (area under the curve: 0.795, 95% confidence interval 0.749–0.841, p < 0.001). Conclusion Syntax score may be helpful to identify for patients who would develop atrial fibrillation in the setting of ACS.