Open AccessLeft bundle branch block: Epidemiology, etiology, anatomic features, electrovectorcardiography, and classification proposal
Author(s) -
PérezRiera Andrés R.,
BarbosaBarros Raimundo,
de Rezende Barbosa Marianne P. C.,
DaminelloRaimundo Rodrigo,
de Abreu Luiz C.,
Nikus Kjell
Publication year - 2019
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12572
Subject(s) - medicine , left bundle branch block , cardiology , etiology , magnetic resonance imaging , bundle branch block , electrical conduction system of the heart , electrocardiography , heart failure , radiology
In left bundle branch block (LBBB), the ventricles are activated in a sequential manner with alterations in left ventricular mechanics, perfusion, and workload resulting in cardiac remodeling. Underlying molecular, cellular, and interstitial changes manifest clinically as changes in size, mass, geometry, and function of the heart. Cardiac remodeling is associated with progressive ventricular dysfunction, arrhythmias, and impaired prognosis. Clinical and diagnostic notions about LBBB have evolved from a simple electrocardiographic alteration to a critically important finding affecting diagnostic and clinical management of many patients. Advances in cardiac magnetic resonance imaging have significantly improved the assessment of patients with LBBB and provided additional insights into pathophysiological mechanisms of left ventricular remodeling. In this review, we will discuss the epidemiology, etiologies, and electrovectorcardiographic features of LBBB and propose a classification of the conduction disturbance.