Open AccessRelationship between QT and JT peak interval variability in prepubertal children
Author(s) -
Takeuchi Yuka,
Omeki Yumi,
Horio Kayo,
Nishio Miki,
Nagata Rina,
Oikawa Shota,
Mizutani Yuri,
Nagatani Arisa,
Funamoto Yuri,
Uchida Hidetoshi,
Fujino Masayuki,
Eryu Yoshihiko,
Boda Hiroko,
Miyata Masafumi,
Hata Tadayoshi
Publication year - 2017
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12444
Subject(s) - medicine , qt interval , heart rate variability , repolarization , cardiology , ventricular repolarization , heart disease , correlation , heart rate , blood pressure , electrophysiology , mathematics , geometry
Background The QT variability index ( QTVI ) is a noninvasive index of repolarization lability that has been applied to subjects with cardiovascular disease. QTVI provides a ratio of normalized QT variability to normalized heart rate variability, and therefore includes an assessment of autonomic nervous activity. However, measurement of QT time is particularly difficult in children, who exhibit physiologically high heart rates compared with adults. In this study, we developed a set of standard values of J‐point to Tpeak interval ( JT p) for infants by age, and assessed the correlation of QTVI with the JT p variability index ( JT p VI ). Methods Subjects included 623 infants and children (0–7 years of age) without heart disease and 57 healthy university students. All subjects were divided into three groups by age. QTVI and JT p VI were calculated based on an electrocardiogram, and age‐specific standard values, a gender‐specific classification, and a standard growth curve were constructed. Results JT p VI markedly decreased in infancy and slowly decreased thereafter, reaching adult values by school age. There was also a strong correlation of JT p VI with QTVI ( r = .856). Conclusions JT p can be used to evaluate the variability of the repolarization time in healthy infants, and may be useful for detection of early repolarization abnormalities.