
The Effect of Diuresis on the Paced QRS Complexes in Pacing‐Dependent Patients with Heart Failure
Author(s) -
Sheng Fuqiang,
Chen Bin,
He Maorong,
Zhang Meilin,
Shen Guoying,
Zhao Xiaowei
Publication year - 2016
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12286
Subject(s) - qrs complex , medicine , diuresis , heart failure , cardiology , diuretic , body weight , electrocardiography , anesthesia , kidney
Background Augmentation of the amplitude of QRS complexes with diuretic therapy for patients with congestive heart failure has been well documented. However, the effect of diuresis on the paced QRS complexes in pacing‐dependent patients with heart failure is scarce. Objective To investigate the effect of diuresis on the paced QRS complexes in pacing‐dependent patients with heart failure. Method Thrity‐two consecutive pacing‐dependent patients with heart failure were enrolled in this study. Before and after diuresis, the sums of paced QRS amplitude of leads I+II (ΣpQRS I+II ), six limb leads (ΣpQRS 6L ), leads V 1 –V 3 (ΣpQRS V1‐V3 ), leads V 4 –V 6 (ΣpQRS V4‐V6 ), leads V 1 –V 6 (ΣpQRS V1‐V6 ), and lead aVR (pQRS aVR ), paced QRS duration (pQRS d ), paced QT intervals (pQT) and the body weight of each patient were measured, then the % changes (Δ%) in paced electrocardiogram (ECG) variables and the Δ% in body weight were evaluated. Results Compared with before diuresis, paced ECG variables significantly increased and body weight significantly decreased after diuresis, Δ% in paced QRS amplitude(s) in all ECG variables (ΣpQRS I+II, ΣpQRS 6L, ΣpQRS V1‐V3 , ΣpQRS V4‐V6 , ΣpQRS V1‐V6 , and pQRS aVR ) correlated well with Δ% in body weight (r = 0.416, r = 0.849, r = 0.901, r = 0.371, r = 0.837, r = 0.619, and P = 0.018, P < 0.001, P < 0.001, P = 0.037, P < 0.001, P < 0.001), while there was no correlation between Δ% in pQRS d and pQT and Δ% in body weight. Conclusions The changes in amplitude of paced QRS complexes may be useful for the monitoring of therapy of pacing‐dependent patients with heart failure.