Open AccessA Predictive Study of the Dynamic Development of the P‐Wave Terminal Force in Lead V 1 in the Electrocardiogram in Relation to Long‐Term Prognosis in Non–ST‐Segment Elevation Acute Coronary Syndrome Patients during Hospitalization
Author(s) -
Li Qiao,
Gu LiDan,
Zhang Chen,
Liu Wei,
Peng Yong,
Chai Hua,
Xu YuanNing,
Wei JiaFu,
Chen Mao,
Huang DeJia
Publication year - 2015
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12254
Subject(s) - cardiology , medicine , acute coronary syndrome , electrocardiography , lead (geology) , myocardial infarction , geomorphology , geology
Background Changes in the ECG indicator PtfV 1 reflect left atrial pressure and left ventricular diastolic function in NSTE‐ACS patients during hospitalization. The value of PtfV 1 in the evaluation of long‐term prognosis in NSTE‐ACS is still not clear. The purpose of this study was to investigate the relationship between the dynamic changes in P‐wave terminal force in lead V 1 (PtfV 1 ) in the ECG of non–ST‐segment elevation acute coronary syndrome (NSTE‐ACS) patients during hospitalization and the long‐term major adverse cardiovascular events (MACEs) of patients. Methods A total of 595 patients who received coronary angiography and were confirmed as NSTE‐ACS in the coronary heart disease database of Department of Cardiology of West China Hospital were continuously included. The PtfV 1 and other clinical data at admission and discharge were collected and dynamically observed. The end events of follow‐up observation were MACEs. Results Follow‐up was performed on 595 patients for 24.71 ± 1.95 months. There were 127 PtfV 1 (+) and 468 PtfV 1 (–) at admission, and the incidences of MACEs were 14.2% and 11.1%, respectively (P = 0.731). Compared with patients with persistent PtfV 1 (–) ECG at admission and discharge, 53 patients with persistent PtfV 1 (+) ECG at admission and discharge had increased risk for MACEs (HR: 2.221, 95% CI: 1.072–4.601, P = 0.032); 94 patients with new PtfV 1 (+) ECG at discharge also had significantly increased risk for MACEs (HR: 2.993, 95% CI: 1.660–5.397, P = 0.000). Conclusions NSTE‐ACS patients with persistent PtfV 1 (+) ECG indicators at admission and discharge and new PtfV 1 (+) at discharge had significantly increased risk of MACEs.