Open AccessThe Assessment of Relationship between Fragmented QRS Complex and Left Ventricular Wall Motion Score Index in Patients with ST Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention
Author(s) -
Uslu Nevzat,
Gul Mehmet,
Cakmak Huseyin Altug,
Atam Ali,
Pusuroglu Hamdi,
Satilmisoglu Hulusi,
Akkaya Emre,
Aksu Hale Unal,
Kalkan Ali Kemal,
Surgit Ozgur,
Erturk Mehmet,
Aksu Huseyin,
Eksik Abdurrahman
Publication year - 2015
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12180
Subject(s) - medicine , ejection fraction , cardiology , percutaneous coronary intervention , conventional pci , myocardial infarction , mace , st elevation , qrs complex , st segment , heart failure
Objectives Fragmented QRS (fQRS) has been found to be associated with high mortality and arrhythmic events in acute coronary syndromes. Regional systolic function using wall motion score index (WMSI) is an alternative to left ventricular ejection fraction (LVEF) for the assessment of left ventricular systolic function. The aim of this study was to investigate the relation between the presence of fQRS on admission electrocardiogram (ECG) and WMSI in ST elevation myocardial infarction (STEMI) underwent primary coronary intervention (PCI). The in‐hospital and long‐term prognostic significance of persistent fQRS was also evaluated. Methods In this retrospective study, 542 patients with a diagnose of STEMI underwent primary PCI were included. Study patients were divided into two groups according to the presence (n = 153) or absence (n = 389) of a fQRS on admission ECG. Results WMSI was found to be significantly higher in fQRS(+) group compared to the fQRS(–) group (P < 0.001). In multivariete analysis, WMSI was found to be an independent predictor of fQRS, and fQRS was inversely associated with LVEF. The in‐hospital reinfarction (P = 0.003), MACE (P = 0.024), intraaortic balloon pump use (P = 0.014), and advanced heart failure (P < 0.001) were found to be significantly more frequent in the fQRS(+) group. The presence of fQRS on admission was found to be associated with an increase in long‐term cardiovascular mortality (P = 0.028), and long‐term all‐cause mortality (P = 0.022). Conclusion WMSI was significantly related with the presence of the fQRS, which reflects the linking between impairment of regional left ventricular systolic function and the presence of severe myocardial injury in STEMI.