Open AccessComparison of Cardiogoniometry and ECG at Rest versus Myocardial Perfusion Scintigraphy
Author(s) -
Weber Stefan,
Birkemeyer Ralf,
Schultes Dominik,
Grewenig Walter,
Huebner Thomas
Publication year - 2014
Publication title -
annals of noninvasive electrocardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.494
H-Index - 48
eISSN - 1542-474X
pISSN - 1082-720X
DOI - 10.1111/anec.12151
Subject(s) - medicine , scintigraphy , coronary artery disease , cardiology , electrocardiography , ischemia , perfusion , single photon emission computed tomography , myocardial perfusion scintigraphy , nuclear medicine , radiology , myocardial infarction , coronary angiography
Background Cardiogoniometry (CGM) is a novel resting electrocardiac method based on computer‐generated three‐dimensional data derived from cardiac potentials. The purpose of this study was to determine CGM's and electrocardiography's (ECG) accuracy for detecting myocardial ischemia and/or lesions in comparison with stress/rest myocardial perfusion scintigraphy (single photon emission computer tomography [SPECT]). Method A cohort of consecutively enrolled patients (n = 100) with suspected or known coronary artery disease (mean age 67.8 years, 52% female) were examined by CGM and resting ECG before stress/rest myocardial scintigraphy. Results Pathological scintigraphy findings at adenosine stress perfusion (ASP) and/or rest were conclusively identified in 21 patients. Diagnostic sensitivity was 71% for CGM and 24% for ECG, specificity was 70% for CGM and 95% for ECG. Reversible ischemia was diagnosed in 16 of 21 patients with pathological scintigraphy results. In this subgroup, sensitivity was 67% for CGM and 25% for ECG. Conclusions At rest, the sensitivity of a CGM significantly surmounts that of a standard 12‐lead ECG for detection of isolated myocardial ischemia or myocardial lesions revealed by scintigraphy/SPECT; specificity is in a reasonable range. CGM's ease of use and its considerable agreement with the results of myocardial scintigraphy, suggests a possible role for patient screening in the primary care setting.