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Blood biomarkers for HIV infection with focus on neurologic complications—A review
Author(s) -
Hagberg Lars,
Edén Arvid,
Zetterberg Henrik,
Price Richard W.,
Gisslén Magnus
Publication year - 2022
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/ane.13629
Subject(s) - cerebrospinal fluid , medicine , neuroimaging , human immunodeficiency virus (hiv) , intensive care medicine , immunology , pathology , psychiatry
Although clinical examinations, neuroimaging, and cerebrospinal fluid analyses are the most important ways to evaluate the impact of HIV infection on the brain and in diagnosis of opportunistic infections, several blood biomarkers including HIV RNA concentrations, CD4 +T‐cell count, and neurofilament light chain protein (NfL) concentration, along with tests for opportunistic infections can provide important information for clinical decisions.