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Personality disorders in temporal lobe epilepsy: What do they signify?
Author(s) -
Baishya Jitupam,
Ravish Rajiv Keni,
Chandran Anuvitha,
Unnithan Gopeekrishnan,
Me Ramshekhar N.,
Thomas Sanjeev V.,
Radhakrishnan Ashalatha
Publication year - 2020
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/ane.13259
Subject(s) - epilepsy , temporal lobe , personality , personality disorders , population , psychology , big five personality traits , psychiatry , personality changes , medicine , clinical psychology , social psychology , environmental health
Objectives To estimate the prevalence of personality disorders in patients with temporal lobe epilepsy (TLE) with mesial temporal sclerosis (MTS) and compare it with general population and analyze their implications on treatment outcome. Materials and Methods TLE was diagnosed based on clinical history, MRI, and Video EEG data. IPDE‐ICD10 screening questionnaire was applied to investigate personality disorder in 120 subjects, 60 cases, and 60 normal controls. Bear‐Fedio inventory (BFI) was used to study different behavior traits in patients with TLE and controls. Results Prevalence of personality disorders was higher (71.7% in cases versus 38.3% in controls) in patients with TLE compared to controls ( P < .001). Some personality traits like schizoid ( P = .002), dissocial ( P = .001), impulsive ( P = .003), anankastic ( P < .001), anxious ( P < .001), and dependent ( P < .001) personalities were found to have high prevalence in TLE. Personality disorder was higher among those cases who had been tried on more than two antiepileptic drugs (AEDs) ( P = .033) and in those with duration of illness more than 10 years ( P = .026). Cases also showed significantly higher score in BFI for all behavioral traits except for aggression. No significant difference of BFI score was seen based on laterality of epileptic focus, gender, duration of illness, or number of AEDs tried. Conclusion There is a significantly higher prevalence of personality disorders in patients with TLE. Specific interventions for these disorders should be considered at the earliest pari passu with AEDs and surgery.