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Mortality‐specific comorbidity among inpatients with ischemic stroke in West China
Author(s) -
Si Yang,
Xiao Xiaoqiang,
Xiang Shunju,
Guo Jiang,
Yu Nengwei,
Mo Qiangning,
Guo Fuqiang,
Sun Hongbin
Publication year - 2019
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/ane.13108
Subject(s) - medicine , atrial fibrillation , comorbidity , diabetes mellitus , heart failure , stroke (engine) , vascular dementia , disease , cardiology , dementia , vascular disease , mechanical engineering , engineering , endocrinology
Objective This study aimed to investigate the current condition of mortality‐specific comorbidity among hospitalized patients with ischemic stroke. Methods Five‐year data of inpatients with ischemic stroke (IS) were extracted from the hospital medical database. A retrospective review of eighteen mortality‐specific comorbidities in extensively validated Charlson Comorbidity Index (CCI) was carried out for each patient. In addition, the distribution of the CCI‐based prognostic score was calculated. Results A total of 10 331 (male 57.6%) cases with IS were recruited in the present study. The most prevalent mortality‐specific comorbidities from high to low were as follows: peripheral vascular disease (35.1%), diabetes uncomplicated (25.2%),mild liver disease (18.3%), chronic pulmonary disease (14.7%), congestive heart failure (10.8%), atrial fibrillation or flutter (10.3%), diabetes complicated (9.1%), moderate or severe renal disease (7.5%), and dementia (7.1%). High prevalence of comorbidities in the elderly was also noted (31.1% patients with score ≥3). Spearman correlation analysis with a rho of 0.25 ( P < 0.001) showed a mild correlation between the age‐ and the CCI‐based prognostic score. Conclusion High prevalence of peripheral vascular disease, diabetes, liver disease, chronic pulmonary disease, congestive heart failure, atrial fibrillation, or flutter as major contributors to mortality was presented in in‐hospital patients with IS in our area. One‐third of old patients with IS expose high mortality risk with the CCI score ≥3. Early prevention and management of the potential comorbidities are necessary to reduce the mortality.