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Including a subject‐paced trial may make the PASAT more acceptable for MS patients
Author(s) -
Bosnes O.,
Dahl O.P.,
Almkvist O.
Publication year - 2015
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/ane.12385
Subject(s) - paced auditory serial addition test , anxiety , neuropsychology , psychology , cognition , neuropsychological test , depression (economics) , distress , population , working memory , psychiatry , neuropsychological assessment , audiology , clinical psychology , medicine , environmental health , economics , macroeconomics
The Paced Auditory Serial Addition Test (PASAT) is regularly used in the evaluation of cognition in multiple sclerosis (MS). However, the test may impose frustration, distress, and anxiety in patients, which may result in refusal to participate by many patients. Objectives In this study, a subject‐ and experimenter‐paced PASAT was compared and analyzed, with regard to independent measures of cognitive functions, as well as disability, fatigue, depression, and anxiety. Methods A population‐based sample of patients with MS ( n  = 34; mean age 47.2 ± 8.6) was examined with the PASAT, including a subject‐paced condition, in addition to the standard experimenter‐paced conditions using three levels of interstimuli intervals (ISI: 3.0, 2.5, and 2.0 s). A comprehensive set of neuropsychological tests, measures of disease severity, fatigue, anxiety, and depression were studied as potentially associated factors. Results Subject‐ and experimenter‐paced PASAT performance correlated significantly and the subject‐paced administration correlated even higher with measures of information processing speed, executive function, attention, and working memory than standard experimenter‐paced administration of PASAT. Discussion The associations between PASAT performance and measures of fatigue, anxiety, and depression were not significant. Conclusion The results indicate that the altered PASAT procedure measures the same cognitive functions in MS as the standard procedure. At the same time, the altered procedure may make the PASAT more user‐friendly for patients with MS.

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