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Predictors of executive complaints and executive deficits in multiple sclerosis
Author(s) -
Hanssen K. T.,
Beiske A. G.,
Landrø N. I.,
Hessen E.
Publication year - 2014
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/ane.12177
Subject(s) - neuropsychology , executive dysfunction , depression (economics) , executive functions , psychology , multiple sclerosis , multivariate statistics , neuropsychological assessment , rehabilitation , cognition , clinical psychology , expanded disability status scale , cognitive deficit , psychiatry , cognitive impairment , statistics , mathematics , neuroscience , economics , macroeconomics
Objectives To investigate executive complaints and objective executive deficits and their relations to both depression and neurological function in multiple sclerosis ( MS ). Materials and methods One hundred and twenty MS patients participating in multidisciplinary rehabilitation underwent assessment with the E xpanded D isability S tatus S cale ( EDSS ), neuropsychological tests of executive function, self‐report measures of executive function ( BRIEF ‐ A ), and depression ( BDI ‐II). Results Multivariate regression analysis showed that moderate depression and above (BDI‐II > 20) significantly predicted a high degree of subjective executive complaints. Multivariate regression analysis showed that EDSS scores above 4.3 significantly predicted executive cognitive deficit, measured by neuropsychological tests. Conclusion Among the study variables, depression was the strongest predictor of executive complaints. A high degree of neurological disability was the strongest predictor for executive deficit, measured by neuropsychological tests.