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Consistent determinants of post‐stroke health‐related quality of life across diverse cultures: B erlin– I badan study
Author(s) -
Owolabi M. O.
Publication year - 2013
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/ane.12126
Subject(s) - stroke (engine) , quality of life (healthcare) , medicine , gerontology , environmental health , psychology , nursing , engineering , mechanical engineering
Objective Discovery of consistent determinants of post‐stroke health‐related quality of life ( HRQOL ) across different cultures is essential for the development of widely applicable therapeutic models for maximizing HRQOL in stroke patients. The objective of this study was to identify variables with consistent effect on post‐stroke HRQOL across disparate cultures. Patients and methods Detailed socio‐demographic and clinical data were obtained from successive stroke patients (≥1 month post‐stroke) from I badan, N igeria ( n = 100) and B erlin, G ermany ( n = 103). Stroke severity was assessed using the N ational I nstitute of H ealth S troke S cale and stroke levity score, while disability was graded with modified R ankin Scale. HRQOL was measured with the psychometrically robust holistic HRQOL in stroke patients ( HRQOLISP ) instrument. Variables with significant univariate or bivariate relationships to HRQOL were included in the multiple forward stepwise regression analysis at P = 0.05. Results In disparate cultures, marital status (0.091 < P < 0.902) and stroke type (0.357 < P < 0.975) had no significant relationship to HRQOL . In regression models explaining up to 86% of the HRQOL variance in Ibadan and 70% of the HRQOL variance in B erlin; stroke severity, disability, emotional disorder, and sense of purpose in life were the key predictors of HRQOL after stroke ( P < 0.0001 to P < 0.04). Conclusions Based on these consistent determinants, the stroke recovery cycle, a novel therapeutic model aimed at improving sense of purpose and meaning in life after stroke while promoting emotional and physical well‐being, is proposed for further exploration.