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Second to fourth digit ratio and lung function (forced vital capacity): predictors of maximum urinary flow rate after holmium laser enucleation of the prostate
Author(s) -
Park IN.,
Kim T. B.
Publication year - 2019
Publication title -
andrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.947
H-Index - 43
eISSN - 2047-2927
pISSN - 2047-2919
DOI - 10.1111/andr.12564
Subject(s) - medicine , enucleation , prostate , univariate analysis , urology , vital capacity , multivariate analysis , surgery , lung function , lung , cancer , diffusing capacity
Background Maximum urinary flow rate (Qmax) is usually increased after holmium laser enucleation of the prostate (Ho LEP ). However, improvements vary between patients and results regarding potential predictors of Qmax after Ho LEP are inconsistent. Thus, we investigated pre‐operative variables including second to fourth digit ratio (digit ratio) and pulmonary function test ( PFT ) findings as potential predictors of Qmax after Ho LEP . Methods One hundred and ninety‐five consecutive patients with benign prostatic hyperplasia ( BPH ) who underwent Ho LEP were enrolled. Before Ho LEP , PFT s were performed and lengths of second and fourth digits of right hands were measured by a single investigator using a digital vernier caliper. To identify independent predictors of Qmax after Ho LEP , univariate and multivariate analyses were performed using linear regression models. Results Mean age and total prostate volume for all 195 study subjects were 69.4 years and 63.3 mL respectively. Mean pre‐operative and post‐operative Qmax values were 8.7 and 26.2 mL /sec respectively. Univariate analysis showed age ( r = −0.181, p = 0.014), digit ratio ( r = 0.213, p = 0.004), lung function (forced vital capacity ( FVC ): r = 0.218, p = 0.005; forced expiratory volume in 1 sec ( FEV 1): r = 0.166, p = 0.034), pre‐operative Qmax ( r = 0.264, p = 0.000), pre‐operative voided volume ( VV ) ( r = 0.158, p = 0.033), and post‐operative VV ( r = 0.311, p = 0.000) were associated with post‐operative Qmax, whereas multivariate analysis showed that digit ratio (β = 0.285, p = 0.001), FVC (β = 0.340, p = 0.039), and post‐operative VV (β = 0.301, p = 0.000) independently predicted post‐operative Qmax. Conclusions The independent predictors of Qmax after Ho LEP were digit ratio and lung function ( FVC ) as well as post‐operative VV . This means that the higher a man's digit ratio and lung function ( FVC ), the higher his Qmax after Ho LEP .