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The different surrogate measures of adiposity in relation to semen quality and serum reproductive hormone levels among Estonian fertile men
Author(s) -
EhalaAleksejev K.,
Punab M.
Publication year - 2015
Publication title -
andrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.947
H-Index - 43
eISSN - 2047-2927
pISSN - 2047-2919
DOI - 10.1111/andr.12002
Subject(s) - semen quality , sex hormone binding globulin , semen , endocrinology , medicine , testosterone (patch) , body mass index , quartile , waist , semen analysis , hormone , body fat percentage , sperm , biology , andrology , androgen , infertility , pregnancy , confidence interval , genetics
Summary The objective of this study was to investigate the relations of basic semen parameters and reproductive hormones with different surrogate measures of adiposity: body mass index ( BMI ), body fat percentage ( BF %), waist circumference ( WC ) and waist‐to‐height ratio ( WH tR). Standard semen analysis was performed and serum levels of reproductive hormones were measured in 260 male partners of pregnant women at a university hospital andrology centres in Estonia. Quartile analysis revealed that all adiposity markers were negatively related to sex hormone‐binding globulin and total testosterone levels. After adjustment for covariates a high BF %, WC and WH tR were negatively associated with total sperm count. The BF % was also negatively related to semen volume. These significant changes occurred from a BF % ≥ 23.4%, WC > 98 cm and WH tR > 0.54. Next to these changes the BMI was not related to sperm parameters. This study shows that semen quality is affected by central adiposity and confirms earlier findings that adiposity markedly changes serum sex hormone levels. Further studies are required to find out what is the best body composition marker showing most clearly the relationships between adiposity, semen characteristics and sex hormone levels.