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Testicular seminoma with pagetoid spread into the vas deferens: A rare histopathological presentation
Author(s) -
Ambrosini Francesca,
Di Stasio Andrea,
Borra Tiziana,
Cavallone Barbara,
Terrone Carlo,
Serao Armando
Publication year - 2021
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/and.14061
Subject(s) - vas deferens , pagetoid , spermatic cord , testicular cancer , rete testis , medicine , malignancy , seminoma , testicle , orchiectomy , pathology , cancer , surgery , anatomy , epididymis , sperm , andrology , immunohistochemistry , chemotherapy
Testicular cancer, in particular testicular germ cell tumours, is the most common malignancy in young adult men. Defining prognosis and the best therapeutic strategy is challenging since accurate staging could be controversial. We report an unusual case of seminoma with pagetoid spread into the rete testis and, unexpectedly, also within the epithelium of the vas deferens, up to the margin of excision of the spermatic cord. Focussing on the extremely rare pathological finding and the challenge in defining the stage and the best post‐surgical management, we would like to raise some issues about the knowledge gap on this topic.