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Zinc is a strong stimulant of metallothionein synthesis in the ischaemic testis tissue
Author(s) -
Yazğan Betul,
Baltaci Abdulkerim Kasim,
Mogulkoc Rasim,
Avunduk Mustafa Cihat
Publication year - 2021
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/and.14042
Subject(s) - metallothionein , zinc , immunohistochemistry , ischemia , stimulant , medicine , andrology , endocrinology , chemistry , biology , organic chemistry
This study was performed to determine the effect of zinc supplementation effects on metallothionein levels in testis ischaemia‐reperfusion of rats. The experimental groups were designed as Control, Sham, Ischaemia‐Reperfusion (I/R) and I/R + Zinc supplemented. Zinc supplemented as 5 mg/kg day for 3 weeks. Testis tissues were analysed for metallothionein by immunohistochemical staining procedures. Group comparison showed that the zinc‐supplemented ischaemia‐reperfusion group had a significantly higher level of cells strongly stained with metallothionein than all other groups. A general evaluation of the results suggests that zinc supplementation is a strong stimulant of metallothionein synthesis in the ischaemic testis tissue.