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Can low serum brain‐derived neurotrophic factor levels be associated with lifelong premature ejaculation?; A pilot study
Author(s) -
Atik Yavuz T.,
Gokce Ahmet,
Halis Fikret,
Cimen Haci Ibrahim
Publication year - 2020
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/and.13746
Subject(s) - premature ejaculation , brain derived neurotrophic factor , medicine , neurotrophic factors , ejaculation , endocrinology , body mass index , psychology , receptor , psychoanalysis
This study aimed to present the association between the serum level of brain‐derived neurotrophic factor (BDNF) and the lifelong pre‐mature ejaculation (PE). The data of 40 patients with lifelong PE and 40 healthy controls were evaluated prospectively. PE diagnostic tool and patient‐reported outcome measures were performed to the participants. The serum BDNF level measurement was made after the collecting of blood samples in both groups. The mean ± SD age of the PE and control group was 34.43 ± 5.71 and 33.03 ± 3.97 years respectively ( p = .228). Only the participant who has been married included in the study, and there was no difference in the mean marriage duration. In both groups, smoking status, alcohol use and body mass index were similar. The median PE diagnostic tool scores were 15 (11–20), and serum BDNF levels were 225.3 (26.1–689.6) ng/ml in the PE group, 5 (0–9) and 540.9 (102.9–769.2) ng/ml in the control group respectively ( p < .001 for both). The patients with PE had significantly lower serum BDNF levels. Our study suggests that lower serum BDNF levels may be directly related to lifelong PE.