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Evaluation of seminal oxidation–reduction potential in male infertility
Author(s) -
Panner Selvam Manesh Kumar,
Finelli Renata,
Agarwal Ashok,
Henkel Ralf
Publication year - 2021
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/and.13610
Subject(s) - oxidative stress , infertility , semen , male infertility , context (archaeology) , reduction potential , andrology , fertility , redox , semen quality , sperm , medicine , gynecology , biology , chemistry , genetics , pregnancy , environmental health , population , paleontology , inorganic chemistry , organic chemistry
Abstract The role of oxidative stress in male infertility has been broadly recognised, and the search for a new marker to determine the redox environment in semen has gained considerable interest. Oxidation–reduction potential (ORP) or redox potential, is a measure of the electron transfer from antioxidants to oxidants and provides information on the redox balance. In this review, the benefits of ORP as a new oxidative stress marker, the protocol for its evaluation and the importance of its measurement in the context of male infertility are discussed. In association with the standard semen analysis, seminal ORP has been analysed to evaluate semen quality and male fertility status. However, further studies are required to establish its use in assisted reproductive techniques (ART) practice.