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Relationships between total testicular volume, reproductive parameters and surrogate measures of adiposity in men presenting for couple's infertility
Author(s) -
EhalaAleksejev K.,
Punab M.
Publication year - 2018
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/and.12952
Subject(s) - semen , body mass index , testosterone (patch) , waist , infertility , semen analysis , sperm , endocrinology , anthropometry , male infertility , medicine , sex hormone binding globulin , physiology , biology , gynecology , hormone , andrology , pregnancy , androgen , genetics
Summary The objective of this study was to investigate the relationships between total testicular volume ( TTV ), reproductive parameters and adiposity measures: body mass index, waist circumference and waist‐to‐height ratio. Semen analysis was performed, and reproductive hormone levels were measured in 2,672 male patients (mean age 32.6) due to couple's infertility. Significant, positive correlations between semen parameters and the TTV were found. Gonadotrophins were negatively related to the TTV, and testosterone was not related to the TTV . Three anthropometric parameters were negatively correlated to the total sperm count, and sperm concentration seen in men with a TTV of ≤46 ml. In the case of a TTV >46 ml, only the semen volume was inversely correlated with WC and WH tR. These changes occurred from a WH tR ≥0.56, WC ≥102 cm and BMI ≥29 and were more pronounced between WH tR and the TTV . Adiposity was associated with a significant testosterone level decline but did not have a major impact on the gonadotrophin levels. This study shows the divergent results in sperm parameters in different TTV groups in the presence of central adiposity.