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Effects of aqueous root extract of Carpolobia alba G. Don on sexual behaviour in adult male rats
Author(s) -
Kenmogne H.,
Koloko B.,
Hambe C.,
Domkam J.,
Ngaha Njila M.,
Bend E.,
Oundoum Oundoum P.,
Massoma Lembè D.,
Dimo T.
Publication year - 2016
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/and.12678
Subject(s) - ejaculation , erectile dysfunction , adult male , aqueous extract , sexual behavior , distilled water , sperm , traditional medicine , medicine , biology , andrology , chemistry , clinical psychology , chromatography
Summary Several lines say that a number of natural products, mostly plant based, have been claimed to cure male sexual dysfunction. One of such botanicals is Carpolobia alba G. Don which is used in Cameroon to treat erectile dysfunction and related male sexual debilities. However, the traditional claim has not been scientifically tested. Thirty adult male rats (five groups of six animals) were orally treated daily with distilled water, sildenafil citrate (positive control), 75, 150, 300 mg/kg of C. alba G. Don roots aqueous extract. The erection and ejaculation properties were recorded on the first, seventh and fourteenth day of treatment by following copulation settings: number of erections ( NE ), mount frequency ( MF ), intromission frequency ( IF ), ejaculation frequency ( EF ), mount latency ( ML ), intromission latency ( IL ), ejaculation latency ( EL ), average interval of copulation ( AIC ) and post‐ejaculatory interval ( PEI ). The extract resulted in an improvement of copulation parameters through significant reduction ( p < .001) of PEI, ML and IL and significant increase ( p < .001) in the NE, MF, IF, EF, EL and AIC. These results indicate a pro‐erectile and pro‐ejaculatory potential of aqueous root extract of this plant in male rats.