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Comparison of conventional in vitro fertilisation and intracytoplasmic sperm injection outcomes in patients with moderate oligoasthenozoospermia
Author(s) -
Shuai H.L.,
Ye Q.,
Huang Y.H.,
Xie B.G.
Publication year - 2015
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/and.12291
Subject(s) - intracytoplasmic sperm injection , in vitro fertilisation , medicine , gynecology , pregnancy rate , fertilisation , andrology , insemination , infertility , pregnancy , embryo quality , assisted reproductive technology , obstetrics , sperm , reproductive technology , biology , genetics , lactation
Summary The method of choice for assisted reproductive technology treatment in vitro fertilisation ( IVF ) or intracytoplasmic sperm injection ( ICSI ) is usually based on the evaluation of male infertility factors. Decisions for couples with moderate oligoasthenozoospermia ( OA ) are often empirical because uniform treatment criteria are lacking. This study aimed to evaluate the effect of patients with moderate OA treated with conventional IVF and ICSI . A total of 199 couples with moderate OA undergoing their first IVF / ICSI cycle were included in the study. The patients were divided into two groups according to the type of insemination: conventional IVF group ( n = 97) and ICSI group ( n = 102). All patients were randomised to be inseminated either by conventional IVF or ICSI . The fertilisation rate, embryo quality, implantation rate and clinical pregnancy rate were examined. No differences in the fertilisation, implantation and pregnancy rates were observed between conventional IVF and ICSI groups ( P > 0.05). However, the number of good‐quality embryos was significantly higher in the ICSI group than in the IVF group ( P < 0.05). Couples with moderate OA did not influence on the overall clinical outcomes between IVF and ICSI treatments, and a negative influence by ICSI on blastocyst development was not confirmed.