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Chronic consumption of alcohol and sperm parameters: our experience and the main evidences
Author(s) -
Condorelli R. A.,
Calogero A. E.,
Vicari E.,
La Vignera S.
Publication year - 2015
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/and.12284
Subject(s) - semen quality , infertility , male infertility , alcohol consumption , recreational drug , medicine , alcohol , semen , ethanol , sperm , physiology , gynecology , andrology , biology , pregnancy , pharmacology , drug , genetics , biochemistry
Summary The present article describes the recent clinical experience and the main clinical and experimental evidences on this topic. In the first part, we present retrospective data collected over the last year on the semen quality and hormonal characteristics of the alcohol consumers evaluated in our centre. In the second part, we describe the mechanisms by which chronic alcohol intoxication impairs the testicular function (evidences for an ethanol‐mediated effect at pre‐testicular/testicular and post‐testicular level). In the third part, we present data on ethanol taken a male risk factor of infertility, being present as one among other recreational drugs (also called lifestyle). Finally, is discussed the role of individual susceptibility factors and other variables.