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Influence of propofol‐based total intravenous anaesthesia on peri‐operative outcome measures: a narrative review
Author(s) -
Irwin M. G.,
Chung C. K. E.,
Ip K. Y.,
Wiles M. D.
Publication year - 2020
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/anae.14905
Subject(s) - propofol , medicine , anesthesia , narrative review , neurosurgery , anesthesiology , intensive care medicine , surgery
Summary Propofol‐based total intravenous anaesthesia is well known for its smooth, clear‐headed recovery and anti‐emetic properties, but there are also many lesser known beneficial properties that can potentially influence surgical outcome. We will discuss the anti‐oxidant, anti‐inflammatory and immunomodulatory effects of propofol and their roles in pain, organ protection and immunity. We will also discuss the use of propofol in cancer surgery, neurosurgery and older patients.