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Intelligence quotient scores at the age of 6 years in children anaesthetised before the age of 5 years
Author(s) -
Heer I. J.,
Tiemeier H.,
Hoeks S. E.,
Weber F.
Publication year - 2017
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/anae.13687
Subject(s) - medicine , intelligence quotient , cohort , pediatrics , cognition , association (psychology) , logistic regression , anesthesia , demography , psychiatry , philosophy , epistemology , sociology
Summary We analysed the association of independent variables with non‐verbal cognition at 6 years in children with complete data (3441 from a cohort of 9901), of whom 415 were anaesthetised before the age of 5 years. Using multivariable regression, cognition was reduced by a mean (95% CI ) score for children: anaesthetised before the age of 5 years, 2.1 (0.7–3.5), p = 0.004; born prematurely, 9.8 (4.1–15.4), p = 0.001; whose mothers smoked while pregnant, 2.3 (0.8–3.8), p = 0.004; whose mothers had lower IQ scores, 0.3 (0.2–0.3) for each unit reduction in maternal IQ , p < 0.0001. The association of child IQ with exposure to anaesthetic drugs was sensitive to missing data.