The association between pre‐operative variables, including blood pressure, and postoperative kidney function

Summary We used multivariate analyses to assess the association of pre‐operative variables with kidney function in 41,523 adults after scheduled surgery in a single large academic hospital. Eight variables were independently associated with a reduction in postoperative estimated glomerular filtration rate: pre‐operative renal function; age; ASA physical status; cardiac failure; anaemia; cancer; type of surgery; and the lowest quartile of pre‐operative mean arterial blood pressure (< 71 mmHg). The estimated glomerular filtration rate fell by a mean (95% CI ) of 2.7 (0.04–5.40) ml.min −1 .1.73 m −2 for patients with a pre‐operative mean arterial pressure < 71 mmHg, p = 0.047. The same variables and male sex were associated with postoperative acute kidney injury. The odds ratio (95% CI ) for acute postoperative kidney injury was 1.9 (1.2–2.9) for patients with a pre‐operative mean arterial blood pressure < 71 mmHg, p = 0.005.