Premium
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children
Author(s) -
Makkar J. K.,
Bhatia N.,
Bala I.,
Dwivedi D.,
Singh P. M.
Publication year - 2016
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/anae.13230
Subject(s) - dexmedetomidine , propofol , medicine , anesthesia , sedation , emergence delirium , desflurane , delirium , incidence (geometry) , saline , general anaesthesia , sevoflurane , intensive care medicine , physics , optics
Summary Emergence delirium is a common problem in children recovering from general anaesthesia. We performed a study comparing emergence characteristics in 100 patients who were randomly allocated to receive either 0.3 μg.kg −1 dexmedetomidine, 1 mg.kg −1 propofol or saline 0.9% and undergoing infra‐umbilical surgery. The Pediatric Anesthesia Emergence Delirium scale was used to grade emergence delirium. Emergence delirium occurred in 9.4% of children in the dexmedetomidine group compared with 13.9% in the propofol group and 40.6% in the control group (p = 0.004). In the dexmedetomidine group, sedation occurred in 62.5% of children at 10 min after transfer to the recovery area, compared with 44.4% in the propofol group and 12.5% in the control group (p = 0.010). We conclude that dexmedetomidine significantly reduced the incidence of emergence delirium but this was at the expense of a greater incidence of sedation in the recovery period.