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Strength and sensation after epidural ropivacaine in men and women
Author(s) -
Gan S.,
Song L.,
Chen W.,
Feng Z.,
Li Y.,
Zhang J.,
Zhu S.
Publication year - 2015
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/anae.13085
Subject(s) - medicine , dermatome , ropivacaine , anesthesia , sensation , pain sensation , surgery , biology , neuroscience
Summary We injected 15 ml epidural ropivacaine in 30 men and 30 women to determine the median dose required to impair a straight‐leg raise. We started at a concentration of 0.425%, increasing the concentration by 0.025% after an ineffective injection and decreasing the concentration by 0.025% after an effective injection. The median (95% CI) concentration of ropivacaine that prevented straight‐leg raise within 30 min of injection was 0.43% (0.41–0.45%) in men and 0.40% (0.39–0.41%) in women, p = 0.001. There were no differences in dermatome levels for loss of pinprick and cold sensation between men and women.