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Evaluation of changes in tidal volume during mask ventilation following administration of neuromuscular blocking drugs
Author(s) -
Sachdeva R.,
Kannan T. R.,
Mendonca C.,
Patteril M.
Publication year - 2014
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/anae.12677
Subject(s) - rocuronium , medicine , propofol , anesthesia , ventilation (architecture) , neuromuscular blockade , tidal volume , fentanyl , isoflurane , neuromuscular blocking agents , neuromuscular monitoring , respiratory minute volume , respiratory system , mechanical engineering , engineering
Summary The practice of checking the ability to mask ventilate before administering neuromuscular blocking drugs remains controversial. We prospectively evaluated the changes in the expired tidal volume during pressure‐controlled ventilation (two‐handed mask ventilation technique) as a surrogate marker to assess the ease of mask ventilation following administration of rocuronium. After informed consent, 125 patients were anaesthetised using a standard induction technique consisting of fentanyl, propofol and rocuronium, with anaesthesia then maintained with isoflurane in oxygen. The mean ( SD ) expired tidal volume before administration of rocuronium increased by 61 (13) ml at 2 min following onset of neuromuscular block (p < 0.001). This supports the concept that neuromuscular blockade induced by rocuronium facilitates mask ventilation.